Predictors of Persistent Somatic Symptoms in the General Population: A systematic review of cohort studies.

The results provide strong evidence for factors from all dynamic biopsychosocial domains, although interpersonal and health behavioral factors are relatively under investigated. Thus, evidence suggests that reduction of predictors of PSS onset to a specific factor/domain may be too restrictive. There is no evidence that this differs per PSS-subtype. Exploring all domains and measuring common factors across subtypes is essential to improve the clinical course of PSS.