A Single-Cell Atlas of Small Airway Disease in Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study.

Steven BoothAileen HsiehLeila Mostaco-GuidolinHyun-Kyoung KooKeith WuFatemeh AminazadehChen Xi YangDaniela QuailYuhong WeiJoel D CooperPeter D ParéJames C HoggDragoş Mihai VasilescuTillie-Louise Hackett

Published in: American journal of respiratory and critical care medicine (2023)

Loss of TB alveolar attachments through degradation of elastin, is an important feature of small airway obstruction in mild/moderate COPD, emphasizing the need for early diagnosis and treatment.

Keyphrases

single cell
rna seq
chronic obstructive pulmonary disease
machine learning
mycobacterium tuberculosis
physical activity
lung function
deep learning