Defining trajectories of response in patients with psoriasis treated with biologic therapies.
Nophar GeifmanN AzadbakhtJ ZengT WilkinsonN DandI BuchanD StockenPaola Di MeglioR B WarrenJ N BarkerN J ReynoldsM R BarnesC H SmithChristopher Ernest Maitland GriffithsN Peeknull nullPublished in: The British journal of dermatology (2021)
These subgroups, defined by change in disease over time, may be indicative of distinct endotypes driven by different biological mechanisms and may help inform the management of patients with psoriasis. Future work will aim to further delineate these mechanisms by extensively characterizing the subgroups with additional molecular and pharmacological data.