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Adult-onset type 1 diabetic patients with less severe clinical manifestation have less risk DR-DQ genotypes than childhood-onset patients.

Wenqian RenDaizhi YangZiyu JiangYingxin XianQianwen HuangSihui LuoXueying ZhengJinhua YanWen XuBin YaoCong-Yi WangJin-Xin BeiLeif GroopJanelle A NobleJian-Ping Weng
Published in: Diabetes/metabolism research and reviews (2020)
Adult-onset type 1 diabetic patients with susceptible haplotypes (DR3, DR4 or DR9) were more likely to carry protective DR-DQ haplotypes than childhood-onset patients, which suggested the association between less risk DR-DQ genotypes and the less severe clinical manifestation in adult-onset patients.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • chronic kidney disease
  • type diabetes
  • peritoneal dialysis
  • editorial comment
  • prognostic factors
  • patient reported outcomes
  • young adults
  • patient reported