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Associations of gene polymorphisms in interferon-alpha signature-related genes with autoimmune thyroid diseases.

Jiunn-Diann LinShun-Fa YangYuan-Hung WangWen-Fang FangKam-Tsun TangChao-Wen Cheng
Published in: Clinical endocrinology (2019)
The SNP rs1061501 of IRF7 was associated with the development of GD. Serum IFN-α levels were associated with HT, while they might modify the disease status of GD. Moreover, a genetic effect of rs1061501 on regulating serum IFN-α production was observed in HT.
Keyphrases
  • dendritic cells
  • genome wide
  • immune response
  • multiple sclerosis
  • dna methylation
  • copy number
  • drug induced