A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer.
Kathy HanAnthony W FylesTina ShekJennifer CrokeNeesha C DhaniDavid D'SouzaTing-Yim LeeNaz ChaudaryJeffrey P BruceMelania PintilieRob A CairnsDouglass VinesSara PakbazDavid A JaffrayUr MetserMarjan RouzbahmanMichael F MilosevicMarianne KoritzinskyPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Metformin decreased cervical tumor hypoxia in this trial that selected for patients with hypoxic tumor.