Correlation of multiple endpoints in the first-line chemotherapy of advanced gastric cancer: Pooled analysis of individual patient data from Japanese Phase III trials.
Hiroyuki AraiMadoka TakeuchiWataru IchikawaKohei ShitaraYu SunakawaKoji ObaWasaburo KoizumiYuh SakataHiroshi FurukawaYasuhide YamadaMasahiro TakeuchiMasashi FujiiPublished in: Cancer medicine (2023)
Our results reacknowledged the mild surrogacy of PFS and importance of postprogression treatments in patients with AGC receiving first-line chemotherapy. Consistent longer survival outcomes in better RECIST categories suggested that tumor response might be a useful individual-level surrogate.