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Correlation of multiple endpoints in the first-line chemotherapy of advanced gastric cancer: Pooled analysis of individual patient data from Japanese Phase III trials.

Hiroyuki AraiMadoka TakeuchiWataru IchikawaKohei ShitaraYu SunakawaKoji ObaWasaburo KoizumiYuh SakataHiroshi FurukawaYasuhide YamadaMasahiro TakeuchiMasashi Fujii
Published in: Cancer medicine (2023)
Our results reacknowledged the mild surrogacy of PFS and importance of postprogression treatments in patients with AGC receiving first-line chemotherapy. Consistent longer survival outcomes in better RECIST categories suggested that tumor response might be a useful individual-level surrogate.
Keyphrases
  • phase iii
  • locally advanced
  • open label
  • clinical trial
  • neoadjuvant chemotherapy
  • phase ii
  • electronic health record
  • double blind
  • case report
  • rectal cancer
  • squamous cell carcinoma
  • radiation therapy
  • data analysis