Does HIV pre-exposure prophylaxis use lead to a higher incidence of sexually transmitted infections? A case-crossover study of men who have sex with men in Los Angeles, California.
Matthew R BeymerMichelle A DeVostRobert E WeissRhodri Dierst-DaviesChelsea L ShoverRaphael J LandovitzCorinne BeniasiansAli J TalanRisa P FlynnRobyn KrysiakKayla McLaughlinRobert K BolanPublished in: Sexually transmitted infections (2018)
There were significant increases in rectal chlamydia and syphilis diagnoses when comparing the periods directly before and after PrEP initiation. However, only 28% of individuals had an increase in STIs between periods. Although risk compensation appears to be present for a segment of PrEP users, the majority of individuals either maintain or decrease their sexual risk following PrEP initiation.