Impact of posaconazole prophylaxis and antifungal treatment on BAL GM performance in hematology malignancy patients with febrile neutropenia: a real life experience.
Nilüfer Aylin Acet ÖztürkDilara Ömer-TopçuKübra Vurat AcarÖzge Aydın-Güçlüİbrahim Ethem PınarEzgi DemirdöğenAslı Görek-DilektaşlıEsra KazakVildan ÖzkocamanAhmet UrsavasFahir ÖzkalemkaşBeyza EnerRıdvan AliHalis AkalınPublished in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (2023)
Our study shows that posaconazole prophylaxis and active short-term (3 days) antifungal treatment do not significantly affect overall diagnostic performance of GM measurements in bronchoalveolar lavage and bronchial lavage samples. However, using different cut-off values for patients receiving active treatment might be suggested to increase sensitivity.
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