Single-cell transcriptomics identify TNFRSF1B as a novel T-cell exhaustion marker for ovarian cancer.

Yan GaoHui ShiHongyu ZhaoMengcheng YaoYue HeMei JiangJie LiZhefeng LiShaofei SuTao LiuChenghong YinXuebin LiaoWentao Yue

Published in: Clinical and translational medicine (2023)

T cells for predicting OC patient prognosis and the potential therapeutic value of TNFRSF1B. These findings demonstrated the clinical value of TNFRSF1B as a potential immunotherapy target and extended our understanding of factors contributing to immunotherapy failure in OC.

Keyphrases

single cell
rna seq
case report
human health
climate change