Benefit of a more extended pelvic lymph node dissection among patients undergoing radical prostatectomy for localized prostate cancer: A causal mediation analysis.
Marian Severin WettsteinLuke Ajay DavidClinsy PazhepurackelAatif A QureshiAlex ZismanMichael NesbittKarim SabaJaime O Herrera-CaceresChristian D FankhauserArdalan AhmadRobert J HamiltonDaniel EberliAlexandre R ZlottaTullio SulserNeil E FleshnerCédric PoyetAntonio FinelliThomas HermannsGirish S KulkarniPublished in: The Prostate (2021)
Our results not only indicate the utility of ePLND but also that its impact is not restricted to a staging benefit and probably involves a therapeutic benefit mediated through the removal of occult micrometastases.