Targeting mevalonate pathway by zoledronate ameliorated pulmonary fibrosis in a rat model: Promising therapy against post-COVID-19 pulmonary fibrosis.

Reham Hussein MohamedNesma Hussein Abdel HayNesma Mohamed FawzyYomna M TamimM M Doaa KaremDalia Ahmed Yousef YehiaOmnia M Abdel MaksoudDina S Abdelrahim

Published in: Fundamental & clinical pharmacology (2024)

ZA in a dose-dependent manner prevented the pathological effect of CCl4 in the lung by targeting mevalonate pathway. It could be promising therapy against PCPF.

Keyphrases

pulmonary fibrosis
coronavirus disease
sars cov
stem cells
drug delivery
cell therapy
bone marrow
liver fibrosis