Safety of direct oral anticoagulants in patients with advanced liver disease.
Georg SemmlerKatharina PomejDavid Josef Maria BauerLorenz BalcarBenedikt SimbrunnerTeresa BinterLukas HartlJeannette BeckerMatthias PinterPeter QuehenbergerMichael TraunerMattias MandorferJ P LuyendykThomas ReibergerBernhard ScheinerPublished in: Liver international : official journal of the International Association for the Study of the Liver (2021)
Anticoagulants including DOACs should be used with caution in patients with advanced liver disease due to a significant rate of spontaneous bleeding events.