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Characteristics of growth disturbances in patients with intracranial germinomas of different origins.

Bo LiJiayi WangJiongxian YangYanong LiYanwei LiuShuai LiuXiaoguang Qiu
Published in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2021)
Patients with germinoma experienced growth retardation after treatments. The growth disturbance was consistent and more severe in patients with germinoma of sellar origin, while the greatest aggravation was observed in patients with germinoma of basal ganglia origin. Decreasing radiation dose to the HPA may minimize the negative impact of radiotherapy on growth.
Keyphrases
  • early stage
  • radiation therapy
  • squamous cell carcinoma