Indications and results of diagnostic biopsy in pediatric renal tumors: A retrospective analysis of 317 patients with critical review of SIOP guidelines.
Yvan de La MonnerayeJ MichonH PacquementI AertsDaniel OrbachF DozF BourdeautS SarnackiP Philippe-ChometteG AudryA CoulombP FréneauxJ KlijanienkoD BerrebiJ-M ZuckerG SchleiermacherHervé J BrissePublished in: Pediatric blood & cancer (2019)
The use of SIOP criteria to identify patients eligible for presumptive WT neoadjuvant chemotherapy or upfront surgery avoided biopsy in 65% of children and led to a 97% rate of appropriate preoperative chemotherapy. Image-guided CNB is a safe and accurate diagnostic procedure. The relevance of SIOP biopsy criteria might be improved by using an older age threshold (9 years instead of 6 years) and by adding initial tumor volume.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- ultrasound guided
- minimally invasive
- end stage renal disease
- fine needle aspiration
- newly diagnosed
- ejection fraction
- chronic kidney disease
- sentinel lymph node
- squamous cell carcinoma
- prognostic factors
- young adults
- patients undergoing
- physical activity
- peritoneal dialysis
- rectal cancer
- high resolution
- radiation therapy
- early stage
- clinical practice
- coronary artery disease
- patient reported
- patient reported outcomes
- community dwelling