Early Local Therapy for the Primary Site in De Novo Stage IV Breast Cancer: Results of a Randomized Clinical Trial (EA2108).
Seema Ahsan KhanFengmin ZhaoLori J GoldsteinDavid CellaMark BasikMehra GolshanThomas B JulianBarbara A PockajChristine A LeeWajeeha RazaqJoseph A SparanoGildy V BabieraIrene A DySarika JainPaula SilvermanCarla S FisherAmye J TevaarwerkLynne I WagnerGeorge W SledgePublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
Early locoregional therapy for the primary site did not improve survival in patients presenting with metastatic breast cancer. Although it was associated with improved locoregional control, this had no overall impact on quality of life.
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