M2 Macrophage Classification of Colorectal Cancer Reveals Intrinsic Connections with Metabolism Reprogramming and Clinical Characteristics.

Fengxing HuangYouwei WangYu ShaoRunan ZhangMengting LiLan LiuZhao Qiu

Published in: Pharmacogenomics and personalized medicine (2024)

Our research reveals underlying relationships between metabolic phenotypes and immunological profiles and suggests a unique M2 classification technique for CRC. The identified gene signatures may be key factors linking immunity and tumor metabolism, warranting further investigations.

Keyphrases

machine learning
deep learning
genome wide
copy number
dna methylation
gene expression
genome wide identification
transcription factor