Global Representation of Heart Failure Clinical Trial Leaders, Collaborators, and Enrolled Participants: A Bibliometric Review 2000-2020.

Regions disproportionately burdened with HF are under-represented in HF trial leadership, collaboration, and enrolment. RCT leadership outside Europe and North America is independently associated with participant enrolment in under-represented regions. Increasing research capacity outside Europe and North America could enhance trial diversity and generalizability.