Baseline associations between biomarkers, cognitive function, and self-regulation indices in the Cognitive and Self-regulatory Mechanisms of Obesity Study.
Misty A W HawkinsNatalie G KeirnsAmanda N BaraldiHarley M LaymanMadison E StoutCaitlin E SmithJohn GunstadDeana A HildebrandKathleen D VohsWilliam R LovalloPublished in: Obesity science & practice (2021)
In adults with overweight/obesity entering a weight loss treatment study: (1) elevated WC and associated glycemic impairment were negatively associated with cognition, (2) poorer executive function and reading abilities were associated with poorer glycemic control, and (3) objectively measured cognitive functions were unrelated to self-reported/behavioral measures of self-regulation. Such findings increase understanding of the relationships between adiposity, biomarkers, cognition, and self-regulation at treatment initiation and may ultimately inform barriers to successful obesity treatment response.
Keyphrases
- weight loss
- glycemic control
- type diabetes
- insulin resistance
- bariatric surgery
- weight gain
- metabolic syndrome
- roux en y gastric bypass
- gastric bypass
- physical activity
- blood glucose
- high fat diet induced
- body mass index
- white matter
- mild cognitive impairment
- multiple sclerosis
- transcription factor
- replacement therapy