Long-term follow-up of patients with anti-cyclic citrullinated peptide antibody-positive connective tissue disease: a retrospective observational study including information on the HLA-DRB1 allele and citrullination dependency.
Takeshi IwasakiShuichiro NakaboChikashi TeraoKosaku MurakamiRan NakashimaMotomu HashimotoYoshitaka ImuraNaoichiro YukawaHajime YoshifujiYasuo MiuraKimiko YurugiTaira MaekawaMyrthe A M van DelftLeendert A TrouwTakao FujiiTsuneyo MimoriKoichiro OhmuraPublished in: Arthritis research & therapy (2020)
Anti-CCP-positive non-RA CTD patients rarely developed RA. HLA-DRB1 SE and anti-CCP antibody titers may facilitate the differentiation of RA-overlapping CTD from anti-CCP-positive non-RA CTD.