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Inhibition of Fap Promotes Cardiac Repair by Stabilizing BNP.

Yuxi SunMengqiu MaDandan CaoAncheng ZhengYiying ZhangYang SuJianfang WangYanhua XuMi ZhouYansong TangYifan LiuTeng MaAoyuan FanXiaoying ZhangQiaoling ZhuJiachen QinChunyang MoYawei XuLi ZhangDachun XuRui Yue
Published in: Circulation research (2023)
This study identifies Fap as a negative regulator of cardiac repair and a potential drug target to treat MI. Inhibition of Fap stabilizes BNP to promote angiogenesis and cardiac repair.
Keyphrases
  • left ventricular
  • emergency department
  • genome wide
  • heart failure
  • vascular endothelial growth factor
  • risk assessment
  • atrial fibrillation
  • human health
  • adverse drug