Do Cognitive Subtypes Exist in People at Clinical High Risk for Psychosis? Results From the EU-GEI Study.
George GiffordAlessia AvilaMatthew J KemptonPaolo Fusar-PoliRobert A McCutcheonFiona CouttsStefania TogninLucia ValmaggiaLieuwe de HaanMark van der GaagBarnaby NelsonChristos PantelisAnita Riecher-RösslerRodrigo BressanNeus Barrantes-VidalMarie-Odile KrebsBirte GlenthøjStephan RuhrmannGabriele SachsBart P F RuttenJim Van Osnull Eu-Gei High Risk StudyPhilip McGuirePublished in: Schizophrenia bulletin (2024)
Stratifying patients according to cognitive performance has the potential to inform clinical care. However, we did not find evidence of cognitive clusters in this CHR-P sample. We suggest that care needs to be taken in inferring the existence of distinct cognitive subtypes from unsupervised learning studies. Future research in CHR-P samples could explore the existence of cognitive subtypes across a wider range of cognitive domains.