Acute ischemic stroke thrombi have an outer shell that impairs fibrinolysis.
Lucas Di MeglioJean-Philippe DesillesVéronique OllivierMialitiana Solo NomenjanaharySara Di MeglioCatherine DeschildreStéphane LoyauJean-Marc OlivotRaphaël BlancBasile OndzeMarie-Christine BoutonJean-Baptiste MichelMartine Jandrot-PerrusBenoît Ho-Tin-NoéMikael MazighiPublished in: Neurology (2019)
Irrespective of their etiology and despite their heterogeneity, intracranial thrombi causing LVO have a core shell structure that influences their susceptibility to thrombolysis.