Clostridioides difficile: innovations in target discovery and potential for therapeutic success.

Tanya M MonaghanAnna M SeekatzBenjamin Harvey MullishClaudia C E R Moore-GillonLisa F DawsonAmmar AhmedDina H KaoWeng C Chan

Published in: Expert opinion on therapeutic targets (2021)

Considerable progress has been made in the development of new anti-CDI drug candidates. Nevertheless, a greater comprehension of CDI pathogenesis and host-microbe interactions is beginning to uncover potential novel therapeutic targets, which can be exploited to plug gaps in the CDI drug discovery pipeline.

Keyphrases

drug discovery
clostridium difficile
small molecule
high throughput
emergency department
adverse drug
single cell