Effect of SGLT2 inhibitors on cardiovascular, renal and safety outcomes in patients with type 2 diabetes mellitus and chronic kidney disease: A systematic review and meta-analysis.
Tadashi ToyamaBrendon L NeuenMin JunToshiaki OhkumaBruce C NealMeg J JardineHiddo L HeerspinkMuh Geot WongToshiharu NinomiyaTakashi WadaVlado PerkovicPublished in: Diabetes, obesity & metabolism (2019)
Currently available data suggest that, despite only modest reductions in glycated haemoglobin, SGLT2 inhibitors reduce the risk of cardiovascular and renal outcomes in patients with T2DM and CKD, without clear evidence of additional safety concerns.