Mouse blood cells types and aging prediction using penalized Latent Dirichlet Allocation.

Xiaotian WuYee Voan TeoNicola NerettiZhijin Wu

Published in: BMC genomics (2024)

pLDA learns a dimension reduced representation of the expression profile. This representation allows identification of cell types and has predictability of the age of cells.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
stem cells
oxidative stress
cell therapy
cell proliferation
bone marrow
neural network