Prenatal and preimplantation genetic diagnosis for single gene disorders: A population-based study from 1977 to 2016.

Alice PoultonSharon LewisLisa HuiJane L Halliday

Published in: Prenatal diagnosis (2018)

Our population-wide analysis has demonstrated a steady demand for PNDx for single gene disorders over the past decade, in contrast to the rapidly increasing utilisation of PGT-M. PGT-M appears to be the preferred testing modality for adult onset disorders.

Keyphrases

genome wide
copy number
pregnant women
magnetic resonance
dna methylation
gene expression
genome wide analysis