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Investigation of chromosomal alterations in patients with Alzheimer's disease in the state of Amazonas, Brazil.

Kledson Moraes NunesDenise Corrêa BenzaquemNatalia Dayane Moura CarvalhoTalísia Nascimento VianezErnanda Raquel de Queirós Gonçalves de Sousa E FernandesCleiton Fantin
Published in: Arquivos de neuro-psiquiatria (2020)
In the control group, no chromosomal changes were found in the karyotypes of these individuals. Therefore, the karyotypes of patients with AD undergo chromosomal alterations at different levels. These findings are being described for the first time in the population of Amazonas, and they highlight the importance of the inclusion of cytogenetic investigations in the routine management of patients with AD.
Keyphrases
  • copy number
  • cognitive decline
  • clinical practice
  • dna methylation