Periostin plays a critical role in the cell cycle in lung fibroblasts.

Tomohito YoshiharaYasuhiro NanriSatoshi NunomuraYukie YamaguchiCarol Feghali-BostwickKeiichi AjitoShoichi MurakamiMasaaki MawatariKenji Izuhara

Published in: Respiratory research (2020)

Periostin plays a critical role in the proliferation of lung fibroblasts and the present results provide us a solid basis for considering inhibitors of the periostin/integrin αVβ3 interaction for the treatment of IPF patients.

Keyphrases

cell cycle
end stage renal disease
cell proliferation
ejection fraction
chronic kidney disease
newly diagnosed
idiopathic pulmonary fibrosis
peritoneal dialysis
signaling pathway
patient reported outcomes
combination therapy
patient reported
replacement therapy