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Isorhamnetin induces the paraptotic cell death through ROS and the ERK/MAPK pathway in OSCC cells.

Qian ChenShaojuan SongZhen WangYingqiang ShenLiang XieJing LiLu JiangHang ZhaoXiaodong FengYu ZhouMin ZhouXin ZengNing JiQian-Ming Chen
Published in: Oral diseases (2020)
Our study suggested that the anti-cancer effect of isorhamnetin might trigger paraptosis, which may indicate a new therapeutic approach to OSCC.
Keyphrases
  • cell death
  • cell cycle arrest
  • signaling pathway
  • pi k akt
  • induced apoptosis
  • oxidative stress
  • dna damage
  • endoplasmic reticulum stress