Dihydrophenazine: a multifunctional new weapon that kills multidrug-resistant Acinetobacter baumannii and restores carbapenem and oxidative stress susceptibilities.
Norhan H MahdallyRiham A ElShiekhBathini ThisseraAshraf EltaherAya OsamaMaha MokhtarNoha M ElhosseinyMona T KashefSameh MagdeldinAli M El HalawanyMostafa E RatebAhmed S AttiaPublished in: Journal of applied microbiology (2024)
This work underscores the potential of DHP as a promising new agent with multifunctional roles as both a classical and nonconventional antimicrobial agent that is urgently needed.
Keyphrases
- heat shock
- acinetobacter baumannii
- multidrug resistant
- oxidative stress
- drug resistant
- drug delivery
- gram negative
- cancer therapy
- klebsiella pneumoniae
- pseudomonas aeruginosa
- staphylococcus aureus
- metal organic framework
- ischemia reperfusion injury
- diabetic rats
- escherichia coli
- induced apoptosis
- human health
- risk assessment