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Current review of the management of fistulising perianal Crohn's disease.

Samuel O AdegbolaKapil SahnanCharlene Twum-BarimaNusrat IqbalLillian RezaPhillip LungJanindra WarusavitarnePhil TozerAilsa Hart
Published in: Frontline gastroenterology (2020)
Perianal manifestations of Crohn's disease constitute a distinct disease phenotype commonly affecting patients and conferring an increased risk of disability and disease burden. Much research has gone into management of fistulising manifestations, with biological therapy changing the landscape of treatment. In this article, we discuss the up-to-date surgical and medical management of perianal fistulas, highlighting current consensus management guidelines and the evidence behind them, as well as future directions in management.
Keyphrases
  • healthcare
  • end stage renal disease
  • chronic kidney disease
  • bone marrow
  • risk factors
  • patient reported outcomes
  • mesenchymal stem cells
  • cell therapy