Circulating tumor and invasive cell expression profiling predicts effective therapy in pancreatic cancer.

Kenneth H YuJennifer ParkAvni MittalGhassan K Abou-AlfaImane El DikaAndrew S EpsteinDavid H IlsonDavid P KelsenGeoffrey Y KuJia LiWungki ParkAnna M VargheseJoanne F-L ChouMarinela CapanuBrandon CooperAndrew BartlettDevan McCarthyVineet SangarBrian McCarthyEileen M O'Reilly

Published in: Cancer (2022)

Chemosensitivity assay profiling is a promising tool for guiding therapy in advanced PDAC. Further prospective validation is under way (clinicaltrials.gov NCT03033927).

Keyphrases

circulating tumor
single cell
cell therapy
high throughput
circulating tumor cells
genome wide
cell free
mesenchymal stem cells
transcription factor
replacement therapy
chemotherapy induced