Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1-Wnt/β-catenin-TFE3 feedback loop signalling.

Yajun LuoSiqi HuangJinlai WeiHe ZhouWuyi WangJianguo YangQican DengHao WangZhongxue Fu

Published in: Clinical and translational medicine (2022)

LINC01606 functions as an oncogene to facilitate tumor cell stemness, proliferation and inhibit ferroptosis and is a promising therapeutic target for colon cancer.

Keyphrases

long noncoding rna
cell death
epithelial mesenchymal transition
stem cells
cell proliferation
signaling pathway
cell therapy
cell cycle arrest
single cell
transcription factor
long non coding rna