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Liver transplantation in hepatic myelopathy.

Sencan AcarAyhan DinckanMurat Akyildiz
Published in: Hepatology forum (2022)
Hepatic myelopathy (HMy) is a rare neurological complication of liver cirrhosis that involves spastic paraplegia caused by lateral cord demyelination especially due to the accumulation of some metabolites such as ammonia and manganese. We report a young adult woman presenting with spasticity and paraparesis in extremities after intrahepatic portosystemic shunting (TIPS) application and underwent deceased liver transplantation (LT). A 39-year-old woman underwent deceased LT because of cryptogenic liver cirrhosis. She underwent a TIPS procedure 5 years ago. After that, hepatic encephalopathy and spasticity appeared. She was on the waiting list for 3 years. Neurological findings after LT significantly decreased, but did not return to normal. After the emergence of neurological findings, the earlier LT can provide improvement in neurological findings.
Keyphrases
  • botulinum toxin
  • spinal cord
  • upper limb
  • spinal cord injury
  • young adults
  • cerebral palsy
  • kidney transplantation
  • minimally invasive
  • cerebral ischemia
  • case report
  • early onset
  • room temperature
  • blood brain barrier