A comprehensive motion analysis - consequences for high precision image-guided radiotherapy of esophageal cancer patients.
Catharina T G RoosZohra FaizSabine VisserMargriet DietersHans Paul van der LaanLydia A den OtterJohn T M PlukkerJohannes A LangendijkAntje-Christin KnopfChristina T MuijsNanna M SijtsemaPublished in: Acta oncologica (Stockholm, Sweden) (2020)
Despite relatively constant breathing amplitudes, the variation in the diaphragm position (off-set), and consequently tumor position, was clinically relevant. These motion effects may result in either treatments that miss the target volume, or dose deviations in the form of highly localized over- or underdosed regions.