Transfusion of Adult, but Not Neonatal, Platelets Promotes Monocyte Trafficking in Neonatal Mice.

Preeti MauryaSara K Ture Chen LiKristin M ScheibleKathleen E McGrathJames PalisCraig N Morrell

Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)

These data provide comparative insights into adult and neonatal platelet transfusion-regulated monocyte functions. The transfusion of adult platelets to neonatal mice was associated with an acute inflammatory and trafficking monocyte phenotype that was platelet P-sel dependent and may have an impact on complications associated with neonatal platelet transfusions.

Keyphrases

dendritic cells
cardiac surgery
endothelial cells
sickle cell disease
peripheral blood
high fat diet induced
liver failure
oxidative stress
type diabetes
metabolic syndrome
acute kidney injury
risk factors
young adults
childhood cancer
skeletal muscle
artificial intelligence