Association between depression and epigenetic age acceleration: A co-twin control study.

Chang LiuZeyuan WangQin HuiJack GoldbergNicholas L SmithAmit J ShahNancy MurrahLucy ShallenbergerEmily DiggersJames Douglas BremnerYan V SunViola Vaccarino

Published in: Depression and anxiety (2022)

We identified that depression is associated with higher levels of DNAm age acceleration. Further investigation is warranted to better understand the underlying mechanisms for the potential causal relationship between depression and accelerated aging.

Keyphrases

depressive symptoms
sleep quality
gene expression
dna methylation
human health