Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome.

Peter GeorgesonMichael D WalshMark ClendenningSimin DaneshvarBernard J PopeKhalid MahmoodJihoon E JooHarindra JayasekaraMark A JenkinsIngrid M WinshipDaniel D Buchanan

Published in: Molecular genetics & genomic medicine (2019)

Tumor mutational signatures 6 and 15 and somatic mutation burden were effective in differentiating Lynch-related from non-Lynch sebaceous lesions.

Keyphrases

genome wide
magnetic resonance imaging
soft tissue
copy number
dna methylation
computed tomography
contrast enhanced