Detection of SARS-CoV-2 infection by saliva and nasopharyngeal sampling in frontline healthcare workers: An observational cohort study.
Naomi F WalkerRachel L ByrneAshleigh HowardElissavet NikolaouMadlen FarrarSharon GlynnKaterina S CheliotisAna Isabel Cubas-AtienzarKelly DaviesJesús ReinéZalina Rashid-GardnerEsther L GermanCarla SolórzanoTess BlandamerLisa HitchinsChristopher MyerscoughBradford D GessnerElizabeth BegierAndrea M CollinsMike BeadsworthStacy ToddHelen HillCatherine F HoulihanEleni NastouliEmily R AdamsElena MitsiDaniela M Ferreiranull nullPublished in: PloS one (2023)
HCW are a potential source of SARS-CoV-2 transmission in hospitals and symptom screening will identify the minority of infections. Without routine asymptomatic SARS-CoV-2 screening, it is likely that HCW with SARS-CoV-2 infection would continue to attend work. Saliva, in addition to OP/NP swab testing, facilitated ascertainment of symptomatic and asymptomatic SARS-CoV-2 infections. Combined saliva and OP/NP swab sampling would improve detection of SARS-CoV-2 for surveillance and is recommended for a high sensitivity strategy.