The impact of coronary artery disease and left ventricular ejection fraction on the prognosis of patients with peripheral artery disease.
Takuya TsujimuraOsamu IidaTakayuki IshiharaMasashi FujitaMasaharu MasudaShin OkamotoKiyonori NantoTakashi KandaAkihiro SunagaMitsuyoshi TakaharaMasaaki UematsuPublished in: Internal medicine journal (2018)
The impact of the severity of coronary artery disease (CAD) and left ventricular ejection fraction (LVEF) on the prognosis of patients with peripheral artery disease (PAD) has not been systematically studied. We retrospectively analysed 622 patients with PAD (intermittent claudication (IC): n = 446; critical limb ischaemia (CLI): n = 176). The association of SYNTAX score and LVEF with mortality was analysed using the Cox proportional hazard model. In patients with IC, a high SYNTAX score was significantly associated with mortality, whereas reduced LVEF was significantly associated with mortality in patients with CLI. The prognostic impact of CAD and LVEF appears different between patients with IC and CLI.
Keyphrases
- ejection fraction
- peripheral artery disease
- coronary artery disease
- aortic stenosis
- cardiovascular events
- left ventricular
- percutaneous coronary intervention
- coronary artery bypass grafting
- transcatheter aortic valve replacement
- risk factors
- acute myocardial infarction
- heart failure
- acute coronary syndrome
- hypertrophic cardiomyopathy
- cardiac resynchronization therapy
- cardiovascular disease
- atrial fibrillation
- type diabetes
- high intensity