CaPTure: Calcium PeakToolbox for analysis of in vitro calcium imaging data.
Madhavi TippaniElizabeth A PattieBrittany A DavisClaudia V NguyenYanhong WangSrinidhi Rao SripathyBrady J MaherKeri MartinowichAndrew E JaffeStephanie Cerceo PagePublished in: BMC neuroscience (2022)
CaPTure allows for rapid assessment of neuronal activity in cultured cells at cellular resolution, rendering it amenable to high-throughput screening and phenotypic discovery. The platform can be applied to both human- and rodent-derived neurons and is compatible with many imaging systems.
Keyphrases
- endothelial cells
- high resolution
- induced apoptosis
- high throughput
- small molecule
- spinal cord
- cell cycle arrest
- machine learning
- mass spectrometry
- signaling pathway
- cell death
- endoplasmic reticulum stress
- fluorescence imaging
- blood brain barrier
- induced pluripotent stem cells
- sensitive detection
- cerebral ischemia
- subarachnoid hemorrhage