The use of the circulating cathodic antigen (CCA) urine cassette assay for the diagnosis and assessment of cure of Schistosoma mansoni infections in an endemic area of the Amazon region.
Sergei Rodrigo Magalhães de SousaJoyce Favacho Cardoso NogueiraIsabelle Helena Lima DiasÁlvaro Luan Santana FonsecaVivian FaveroStefan Michael GeigerMartin Johannes EnkPublished in: Revista da Sociedade Brasileira de Medicina Tropical (2020)
Our data show that the POC-CCA test has potential as an auxiliary tool for the diagnosis of Schistosoma mansoni infection, yielding better results than 16 Kato-Katz slides from three different stool samples. However, the immunochromatographic test lacks sufficient specificity and sensitivity for verifying the cure rate after treatment.