Protective effects of Bifidobacterium bifidum FL-228.1 on dextran sulfate sodium-induced intestinal damage in mice.

Rui WangMalina KuermanQingyu CuiXiaoying TianYu ZhouHuaxi YiPimin GongKai LinZhe ZhangTongjie LiuLan-Wei Zhang

Published in: European journal of nutrition (2022)

Bifidobacterium bifidum FL-228.1 may be developed as a promising probiotic for the prevention of intestinal barrier damage via PPARγ/NLRP3/ TLR2 pathways by enhancing Muc2 and Cldn-4.

Keyphrases

oxidative stress
diabetic rats
high glucose
toll like receptor
inflammatory response
immune response
insulin resistance
high fat diet induced
drug induced
type diabetes
endothelial cells
adipose tissue
metabolic syndrome
skeletal muscle