Normal IgH Repertoire Diversity in an Infant with ADA Deficiency After Gene Therapy.
Carolyn H BalohSamiksha A BorkarKai-Fen ChangJiqiang YaoMichael S HershfieldSuhag H ParikhDonald B KohnMaureen M GoodenowJohn W SleasmanLi YinPublished in: Journal of clinical immunology (2021)
Based on deep sequencing, gene therapy resulted in an IgHV repertoire with molecular diversity similar to healthy infants.