Safety and Pharmacokinetics of the Substance of the Anti-Smallpox Drug NIOCH-14 after Oral Administration to Laboratory Animals.
Larisa N ShishkinaOleg Yu MazurkovNikolai I BormotovMaksim O SkarnovichOlga A SerovaNatalia A MazurkovaMaria A SkarnovichAlexander Anatolievich ChernonosovBoris A SelivanovAlexey Ya TikhonovSvetlana G GamaleyGalina G ShiminaGalina M SysoyevaOleg Svyatoslavovich TaranovElena D DanilenkoAlexander P AgafonovRinat A MaksyutovPublished in: Viruses (2023)
Along with the previously determined efficacy against orthopoxviruses, including the smallpox virus, the substance NIOCH-14 was shown to be safe and bioavailable in laboratory animal experiments.