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Lower omental t-regulatory cell count is associated with higher fasting glucose and lower β-cell function in adults with obesity.

Lauren E GyllenhammerJonathan LamTanya L AldereteHooman AllayeeOmid AkbariNamir KatkhoudaMichael I Goran
Published in: Obesity (Silver Spring, Md.) (2016)
Tregs were significantly lower in omental versus both subQ adipose depots. Fewer omental Tregs may have metabolic implications based on depot-specific relationships with higher fasting glucose and lower β-cell function.
Keyphrases
  • insulin resistance
  • blood glucose
  • metabolic syndrome
  • type diabetes
  • adipose tissue
  • cell therapy
  • weight gain
  • skeletal muscle
  • blood pressure
  • peripheral blood
  • mesenchymal stem cells