Cryopreserved clumps of mesenchymal stem cell/extracellular matrix complexes retain osteogenic capacity and induce bone regeneration.

Souta MotoikeMikihito KajiyaNao KomatsuManabu TakewakiSusumu HorikoshiShinji MatsudaKazuhisa OuharaTomoyuki IwataKatsuhiro TakedaTsuyoshi FujitaHidemi Kurihara

Published in: Stem cell research & therapy (2018)

These data indicate that cryopreservation does not reduce the biological properties of C-MSCs because of its abundant type I collagen. More specifically, cryopreserved C-MSCs could be applicable for novel bone regenerative therapies.

Keyphrases

mesenchymal stem cells
bone regeneration
umbilical cord
extracellular matrix
bone marrow
cell therapy
electronic health record
big data
stem cells
data analysis
cord blood
body composition
artificial intelligence
postmenopausal women
soft tissue