Direct C(sp3)-H Cyanation Enabled by a Highly Active Decatungstate Photocatalyst.
Kunsoon KimSeulchan LeeSoon Hyeok HongPublished in: Organic letters (2021)
A highly efficient, direct C(sp3)-H cyanation was developed under mild photocatalytic conditions. The method enabled the direct cyanation of various C(sp3)-H substrates with excellent functional group tolerance. Notably, complex natural products and bioactive compounds were efficiently cyanated.