Dense time-course gene expression profiling of the Drosophila melanogaster innate immune response.

Florencia SchlampSofie Y N DelbareAngela M EarlyMartin T WellsSumanta BasuAndrew G Clark

Published in: BMC genomics (2021)

This high-dimensional dataset enabled the comprehensive study of immune response dynamics through the parallel application of multiple temporal data analysis methods. The well annotated data set should also serve as a useful resource for further investigation of the D. melanogaster innate immune response, and for the development of methods for analysis of a post-stress transcriptional response time-series at whole-genome scale.

Keyphrases

immune response
data analysis
gene expression
drosophila melanogaster
innate immune
dendritic cells
toll like receptor
dna methylation
transcription factor
electronic health record
single cell
big data
machine learning
deep learning
heat shock